Technological eugenics

In my last post, I’ve discussed the more cultural aspect of eugenics, where I’ve explained that it’s already present in society through cultural norms and access to reproductive technology. This type of eugenics is, in my sense, the one that is closest to Galton’s idea of it, where “society” or the government should decide who gets to reproduce and who doesn’t. This is a more authoritarian vision of eugenics because restricts an individual’s access to reproduction. On the other hand, there can be a more individualistic approach to selective reproduction, and it would in my sense be much more respectful of people individual’s rights. An individualistic vision of Galton’s eugenics wouldn’t be very practical, given that It would simply come down to individual people choosing on their own if their genetic material is worthy of being passed down and then for them to choose the best possible genetic partner if they deem themselves worthy to create a  “better” next generation. I could certainly see a community of eugenic enthusiasts doing that, but I don’t believe it would be so different from what already happens when we choose our reproductive partners without necessarily having genetics in mind but still choosing people we find attractive based on desirable traits.

The one technology that turns the tables on individual eugenics is the possibility for genetic screening and embryo selection.  To put it simply, it is the idea that through in vitro fertilization, where multiple embryos are created, it would be possible to genetically test the embryos in order to get their genotypes, from which genes for desirable traits could be selected for or where the presence of genes for undesired traits could be selected against. This idea is usually demonized by the general public, with the typical scenario that people would all want a white blond boy with blue eyes. I believe this example to be a bit unfounded, in the sense that first, skin color is almost necessarily a combination of both parents; therefore, the only way to select against it would be to select the parent, which is something that hasn’t much to do with embryo selection. Second, I honestly have a hard time figuring out how it would be bad to have more blond hair or blue eyes in the next generation aside from an unfounded fear for the commodification of children’s traits, something that already exists when people select their partners in function of their appearance. In the end the only aspect of this scenario that I can imagine becoming a problem is if people start selecting abusively in favor of boys, something that is already happening with selective abortion and that is creating big society problems. However, I believe that the simplest way to prevent it would be to prevent by law geneticists from disclosing gender whenever the genotype is being analysed.

Outside from these critics, this type of eugenics would certainly be a good way to screen for genetic afflictions and to select against them before they become a problem. Sure, one might question the practical elimination of disabled people that it could entail, but unless it were to become mandatory to select against disability, it would still be possible for disabled people to have disabled children, if only by not using embryo selection at all. Considering that my vision of transhumanism is one where it would give more freedom to people, I believe it would be immoral to force it down on anyone. That being said, it would allow parents to be less stressed out about the possibility that their children might be afflicted with a genetic disease, especially if the said disease was known to be running in the family, and spare them from the difficulties of raising a sick or a disabled child when they might not be ready for it.

Outside of selection against undesirable traits, one of the perks of such a technique would be the ability to select in favor of some traits. For example, it could technically be possible to select in favor of a set of genes known to offer protection against some types of cancer. Another one would be to select in favor of genes that are highly correlated with intelligence. All these possibilities would in fact allow us to make sure that the second generation is better (in some aspects) than the first. As long as the technology is available to everyone and not only to a selected few wealthy people, I can only see that as something that goes in the interest of everyone, parents, children and society.

As interesting as this individual vision of eugenic is, it would still means that whatever change it would bring to society, and whatever “variety” of “better” individual it might create would still be limited by the painfully slow procession of generations. In his article about In vitro eugenics, Robert Sparrow (2013) discusses the possibility of creating multiple generations of embryo selections through the use of induced pluripotent cells. Indeed, he foresees the use of any cell to be turned into gametes, therefore making it possible to create multiple generations of embryos without having to wait for them to grow into a sexually mature person. In his assessment of the technology, he evaluates that up to 2 or 3 generations might be created every year, and suppose that, with every passing generation, it would be possible to select in favor of a “better” genotype, which would eventually allow for the creation of an artificially selected embryo that would hold as many desirable traits as possible.

The ethical implications of this are very delicate, and they involve the ethics of creating embryos for the sole purpose research and it raises the question of what is the person created through multiple generations of in vitro eugenics going to be like. One of the main concerns is about how these multiple induction of pluripotent cells and artificial creation of embryo might affect the epigenetics of cells, which might lead to non-viable or dangerously flawed embryos. This issue raises the question: If eugenicists were to create a “flawed” person, a failed experience, how are they supposed to deal with it if they only realize it after birth? The embryo would obviously turn into a person, both morally and legally and the implication of them living a life of suffering as a direct result of the human intervention would be morally unsound. Any attempt at in vitro eugenics should therefore only be done once all the implications of epigenetics were clearly understood and could be included in the assessment of which embryo would be selected for.

Furthermore, one of the main barriers to realizing in vitro eugenics is our understanding of the link that exists between genotype and phenotype. Once believed to be a “one gene=one trait” relationship, traits have now been proven to be the result of incredibly complex relationships between multiple genes, epigenetics and environment. Unless this relationship were to be fully understood, it would be practically impossible to select for desired traits since the trait itself might be encoded in a way that is too complex to be assessed.

I don’t believe eugenics to be morally bad in and by itself. What I do believe is that any technology that makes it possible should be properly framed in order to prevent the ethical hurdles they might create. I also believe that we should steer clear of any Galton type eugenics, which would force people to have children that are seen as “appropriate” for the need of society. Ultimately, I believe that it should rest into parent’s hand to make embryo selection a part of their reproductive strategy, just like it is up to them to choose their partners and to decide if they want to have children or not.

Sources

Sparrow, R. (2014). In vitro eugenics. Journal of medical ethics40(11), 725-731.

Wilkinson, S., & Garrard, E. (2013). Eugenics and the ethics of selective reproduction

One thought on “Technological eugenics

  1. Thoughtful as usual.

    I agree that a small eugenic community would have no effect in choosing the best possible partners. If not chosen by them, they would be chosen by others. But if that community had access to (cheaper) IVF from select donors, or genetic screening, or if the cost of these were reduced to the point of wide adoption?

    Parents without the option of white skin and blond hair might still select for lighter skin and hair from the distribution in their embryos. I also see no problem with this. Some people in the US consider this terribly racist; but if a child is to be born into a racist society, is it morally justified to cause him to suffer less prejudice?

    Sex selection prevented by PGD [not the right acronym in this context] might be practiced by traditional abortion or infanticide. Also, I would like to hear your thoughts on why sex-based selection is immoral. Not that I’m disagreeing. But what if it’s better, from the child’s perspective, in that society, to be male? I should shut up now….

    Parental rights in determining a child’s modification hit an ethical wall if they choose to have a disabled child, over a healthy one. I’ve read of a couple of cases in the deaf community, one blocked, one successful through using a deaf sperm donor. Some people might not restrict themselves to health and intelligence. Tails might become fashionable, for instance; or excessive sexual characteristics.

    Resistance to diabetes, heart disease, dementia, and just about every major disease you can name can be screened for with today’s technology. We have catalogued a long list of good and bad genes. But I believe you are right to question our understanding of genetics, which limit the application of PGD. Without having read Sparrow, we may still be at the stage of waiting for people to reach maturity to assess the effects of our tinkering. By the time we figure out which genes we want, we’ll probably be able to splice them individually anyway.

    Please do keep posting.

    Ian

    Like

Leave a comment